Laugh lines can appear due to age, sun exposure and certain facial expressions, but are mostly caused by loss of skin elasticity due to decreasing hyaluronic acid.

New Flexible Fillers That Really Work

Are you starting to see lines and folds around your nose and mouth? Are you worried that smiling actually makes you look older? We have two new hyaluronic acid dermal fillers from Galderma called Restylane Defyne™ and Restylane Refyne™. While there are other fillers that can plump wrinkles, Refyne and Defyne can create a more natural-looking result than previously possible, especially in the fight against laugh lines!


As we age, our skin loses elasticity and the lines that run from the sides of the nose toward the corners of the mouth (nasolabial folds) and the lines that run from the corners of your mouth toward the chin (marionette lines) become more pronounced. These wrinkles can appear due to age, sun exposure and certain facial expressions, but are mostly caused by loss of skin elasticity due to decreasing hyaluronic acid.

Many fillers are designed to treat aging effects on the face. However, these two are real game changers. Restylane Defyne and Refyne are specifically intended for laugh lines. These next-generation dermal fillers feature Galderma’s cutting-edge XpresHAn Technology™. This new cross-linked hyaluronic acid forms a flexible gel, making these fillers perfect for use in nasolabial folds and marionette lines. They can help restore a more youthful, natural-looking appearance, while allowing you to maintain your natural expressions, and are more effective than the other options available for reducing smile lines.

Restyane Defyne and Refyne are very similar. Restylane Defyne is a slightly firmer dermal filler, providing the added support needed to treat severe wrinkles and folds, and correct more deepened frown, laugh and smile lines. Restylane Refyne is a bit more flexible than Defyne, and is better for treating moderate facial folds and wrinkles. Both fillers support your natural expression for real-life results that maintain natural movement. Some patients benefit the most from a combination of Restylane Defyne and Refyne.

The patient pictured above was treated by Dr. Tanne with one syringe of Restylane Defyne. The patient was thrilled with her results which gave her a significant improvement and still looked very natural.

Results of treatment with these fillers can last up to 12 months, but the real innovation is the flexible gel which produces results that look entirely natural for the first time! These fillers can be tailored to satisfy the specific needs of each patient. Whether you’re smiling, frowning, puckering up or wrinkling your face any which way, the result looks soft and natural, not puffy or stiff.

Of course, these results are always dependent on the skill of the injector. Dr. Tanne has over 15 years of experience with a wide range of injectables. She is renowned for her artistry and skills in this area. A complimentary consultation with Dr. Tanne will help determine the best treatments for you.

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New Flexible Fillers That Really Work